As a loyal HHonors member, I choose the Conrad for my last trip to Chicago. The location is great for shopping and close to many great River North restaurants. The room was nice, clean, modern though a shower only bathroom (which was large.)
Walking out the Rush St side of the hotel, you have to walk under Wabash to get west which isn't ideal but otherwise the location is convenient for River North and just off Michigan Ave. I recommend staying on the west side of Michigan, like the Conrad, to avoid the extra few minutes back to the expressway/airport.