Went to Anna Maria Island for a wedding in October 2012. My wife & I had never been there before and found this Seaside Inn on the internet and decided to try it out. We loved it. Room was clean, Staff was friendly and very knowledgeable about places to go on the island. We stayed on the ground floor where the rooms are perfect size for 2...they can accomodate 4 with a pull out sofa in the room, but that would be tight quarters. It is centrally located on the island and with the free bus service only a short ride to all island attractions.
I'd stay there again if going back to the island and recommend it as a place to stay.