I agree that the place has gotten seedier over the years (this was my 3rd time there.) but it is till a decent place to walk and eat with a lot of choices. I did not see "dive-looking bars" at least along 16th street. The art museum itself is worth a look if you are interested in modern art; it also has a good collection of Native American and Wester art. Sure, the place is not spotless but for one used to big cities it is not awful and better than deserted downtowns (my home town of Rochester, NY; Tampa and Cincinnati for example.) It may have limited interest for families with children, although the museum has kid programs.
If you own or manage LoDo, register now for free tools to enhance your listing, attract new reviews, and respond to reviewers.