The Radisson Blu Hotel Waterfront is a clean and comfortable hotel, great for business travelers. Our room was spotless and comfortable. The staff are great and were very helpful whenever we needed our rental car or had a question. We had room service breakfast our first morning, and it was delicious, reasonably priced for room service, and delivered right at the requested time.
My main quibble with the hotel is the location. It isn't at the V&A Waterfront, which is a long walk away. The shuttle only runs once an hour and wasn't useful for us, since we had 9:00 am tickets to go to Robben Island, and the shuttle doesn't start running until 9:00. We drove our rental car and parked at the Waterfront, which was quite inexpensive compared to parking in most large cities.