I had first booked to stay one night, in the beginning of February 2013, at this beautiful house. I was so pleased with my stay that I booked for another two nights when I returned to Cartagena, one week later. This is definitely the best boutique in the city. (And trust me, I am supposed to know, being the owner of boutique hotels in Granada, Spain.). I find the location in Getsemani, very exotic and very much "old Cartagena", which all adds to the experience. The other districts in inside the walls, are more "clinical" and touristy. Getsemani is better, more colourful and within walking distance of it all. Just around the corner from the hotel you find a wonderful latin bar with live music and dancing "Cafe La Habana". Great "vibe", great drinks and wonderful atmosphere.
Back to Casa Santa Ana....The staff are great and very good suggesting sights to see; restaurants for every taste and valet. They make you a list of places that will last you a week to visit! Breakfast is included and is served in the lush patio; all a la carte and cooked a la minute. Could not be better! They even have a small dipping pool on the roof to cool off.
If you have the budget for it, I suggest you book the Jr. Suite. For a little extra you get a lot.