The Point Hotel is located in the Beyoglu district of Istanbul, about midway between the Hilton Conference Center and Taksim Square, just up the hill a half block from the Hyatt and Intercontinental hotels. It's located in a fashionable district of cafes, nightclubs, restaurants, and hotels in the area north of the Golden Horn waterway and on the European side of the Bosphorus. As such, it's convenient to all conference facilities, but is about a half-hour walk from the historic district or Galata bridge. I thought the location was safe, quiet, and generally convenient: cab rides to the Blue Mosque were short and cost about 15 Lira (7 euro) and the airport was about an hour away and cost 35 Lira (18 Euro) (have the hotel arrange a fixed-price fare for you with the taxi). The shopping at Istiklal is a short walk away, and there is good (not loud) entertainment in the surrounding blocks.
The hotel is a modern, well-maintained facility that makes the most of it's location. The lobby is clean and bright, the staff is friendly and attentive (although they don't speak much english beyond the people in charge of the various areas). Check in was quick, and you should always take a sample of the Turkish Delight that they have out as you pass the desk from the elevators. There it a Guest Services desk that gives good maps and directions, and the staff has taxis parked nearby. There is a lobby bar on a mezannine balcony, but go up to the 9th floor for great views of the Bosphorus and traditional music (and special events like Salsa night). There is a spa and pool on the 2nd floor, but I didn't use it.
The rooms are comfortable and well equipped: the beds are firm (feather pillows) and they provide bottled water, wireless and ethernet internet, local and english channels, and a nice selection of bathroom goods for free. There is an in-room safe and the windows open to let in a nice breeze (and no smells) at night. The bathroom is pleasant and the water is hot and abundant. The staff does a thorough cleaning during the day and a turn-down with chocolate at night. The mnini-bar is outrageous (15 Lira for a small wine), but there are convenience stores a short walk away if you need anything.
Breakfast is a treat: the 9th floor setting gives wonderful sunrise views over the Bosphorus and the northern part of the city, and the food is absolutely among the most varied and abundant I have seen. I especially like the turkish cheeses and cold meats, the sucuk susage, and the hot yogurt soup, but they have breads, eggs, fruits, french toas, and will rpepare hot main dishes to order. Highly recommended (I made the mistake of using the Hilton buffet the first day: it cost 50 Lira for a much lower-quality meal. Absolutely, stay in the hotel and take advantage of this!)
Aside, Istanbul is a wonderful place: life paints into the corners here, and it ranks near the top of my world cities list. The Frommer's guide is very accurate, and I also recommend taking time for a taste of old-world Turkish cuisine and hospitality at the HaciBaba Restaurant, on the left about a block into Istiklal from Taksim square. Take your courage in the bazaars, eat fish under the Galata bridge, do not attempt to drive yourself, and (if you splurge) do have a drink at the top of the nearby Intercontinental Hotel (Sky Bar: 32 Lira for a Mohito but the view is worth it) at sunset to really appreciate the city after dark (lights on the Bosphorous Bridge and ships slipping by in the moonlight are a treat).
In summary, the Point Hotel is a well located, well run gem in the midst of the hotel and convention district: comfortable and complete, it is an ideal base for your exploration or business in the city and provides all the services you will need to have a memorable and enjoyable visit!