I have stayed here with my friends 4 times now. We stay here when we arrive from the states for our 6 month sojourn, and we stay here in the middle when we bounce back to the good old USA for a visa run. The staff is always kind and helpful, no one tries to hustle us to go shopping in a tuk-tuk at some side alley gem shop (as happened at another 5 star hotel) and there aren't ornery cab drivers lurking around the building haranguing you for a ride every 30 seconds. They're out there, but you have to walk way down the street to get to them.
The breakfast is just lovely. Fresh juices, the usual Bangkok international fare of American/European/Asian breakfast choices. And it seems to run forever. We've stumbled down pretty late after a late night arrival and still managed to be fed.
It is very centrally located, and since we know the city pretty well, we can just walk to the Skytrain and get to where we want to go. It's only at the end of the block and not an unpleasant walk. There is a lot of decent shopping right in the area and some indoor malls within walking distance. There are a couple of amazing fitness clubs nearby with amenities I never dreamed of and we also just happened to find a music and sound shop that had really good studio monitors that we picked up for a good price and brought back to our Thai home in the country for production purposes.
All in all, it's a great location. A little off the beaten track and away from the noise of Chitlom or Nana. Very comfortable. They make us feel like friends returning after a long time away. It's very nice.