We recently stayed at the Hampton Inn. The location is great. It's very close to Pismo Beach and to Avila Beach and right off the freeway. It's next to a shopping center with a Trader Joe's & Walmart.
The hotel is very clean and newly remodeled. The workers were very friendly. The breakfast was ok. The waffles tasted like baking soda, but there were plenty of other items like bagels and yogurt. The con is that it is right off the freeway, so you can hear the big rigs late at night.