I recently stayed in a studio executive apartment on the 22nd floor of this hotel, and was quite impressed. The hotel is new and in excellent condition, my room had a great view and was very quiet (almost no street noise, despite being in the very centre of Melbourne) and the small kitchen was functional. I traveled by myself for work and found that the bathroom arrangements worked well, though as other reviewers have noted they're a bit unconventional. The hotel's location is also excellent - trams pass by the front door every five minutes or so, and it takes only about 5 minutes to walk to Burke Street Mall and the cinemas on Collins Street (Federation Square is 10-15 minutes away). All up, I'd stay here again and recommend it strongly.
That said, the hotel does have some flaws. The most annoying of these is the overpriced internet: while I stayed in several Citadines in France and the UK last year which provided in-room wifi for 'free' as part of the base room rate, this hotel charges $6 an hour or $14 a day for access to the internet services in rooms or the foyer. This is likely to be much more expensive than the cost of providing this service, and seems a rip-off (especially for a not-cheap hotel targeted at business travelers). While a less significant issue, the decision to purchase toasters which sound an alarm when the bread is cooked seems ill-advised; on my first morning in the hotel I thought I'd set off the building's fire alarm! (people intending to buy rather than make breakfast should note that the hotel breakfast buffet is absurdly over-priced, and nicer alternatives are available for half the price if you're prepared to walk a block or two). I also found the non-opening windows to be annoying, though the air conditioning was efficient and quiet.