I was allocated a 2 queen bed room with balcony on the Syngrou avenue side of the hotel. I stayed here for 4 nights while visiting Athens and taking a couple of day trips to Aegina Island (40 minutes by boat from the port of Piraeus) and Cape Sounio (2 hours drive). I strongly recommend both.

The Pros:
Large rooms for European standards and comfortable beds
Some rooms have balconies whith view on the Parthenon
Reasonably priced room service
Restaurants: one of the two serves affordable mediteranean food, while the other one is a very nice but pricey Asian restaurant
Good service
A free bus shuttle will take you from the hotel to the center and back every hour.
In-room internet access (not so common in Greece). Wireless Internet is only in the lobby and costs €11/day, while in-room high speed internet over LAN is €22 per day.

The Cons:
The hotel is located on a very noisy main road and is a little too far from the historic center.
Breakfast is unsurprisingly overpriced but a Starbucks is just a block away from the hotel
Far from the subway station - approx 10-15 minute walk

I would recommend this hotel for business or tourism, especially if you are visiting as a family and need a spacious room with two queen beds or if you want a good compromise between comfort and price.
Moving around in Athens from the hotel is easy by taxi, but beware of fraudulent taxis as I encountered 4 of them. Maybe I was just unlucky but it appears this is very common in Athens so ask the hotel before taking a cab to get an idea on how much you should pay to go from one place to another. If the taxi tries to overcharge you just refuse to pay.

My small children children and I travel exstensively throughout Europe and we found the Ledra Marriott Hotel in Athens to be an excellent hotel. The hotel room was large and comfortable. The rooms are solid so the kids can go bizerk and jump on the beds with no complaints from your neighbors. When you reserve your room, request an Acropolis view. The view from the balcony was great especially at night. Also try to get a rate for this hotel that includes breakfast, the breakfast buffet is great but very expensive if not reserved in your hotel rate. The two restaraunts in the hotel for dinner are very expensive and we found ordering room service was the cheapest way to eat at the hotel. The hotel has a outdoor pool on the roof with great views of the city as well. The hotel has a courtesy shuttle bus to the Main Square in Athens and picks you back up near the Hard Rock Cafe in the same area (the big shopping flea market is only a short walk from this drop off point). You can arrange for a Grayline tour bus to pick you up directly from the hotel for a Athens City Tour for no additional fee to your tour trip. The only down side to this great hotel is its location. If you have kids or any health problems you can forget walking to any tourist area/shopping/or any variety of restaraunts from the hotel, it is just simply to far away. You have to take a cab or the shuttle bus. The best thing about this hotel is its friendly and very helpful staff. The hotel staff and the Greek people have made a wonderful impression on us and we will definitely return :)

We were attending a wedding north of Athens in Sept 04 but wanted to stay downtown and see the sites. Our biggest concern was the location of the Marriott but that did not prove to be a concern at all. We walked daily to Parliment Square to meet up with our friends and tried a new route each time. As mentioned in a previous review, we recommend you try different routes each time and you will see more of the city. There is a shuttle as noted above. You can take the subway/tram, it is about a 15-20 minute walk to the closest station (Neos Kosmos) which is handy if you are going outside of downtown. We arrived at 5:30am, and WERE given our room right away (after our complimentary coffee!), which was a great relief after a long trip. The room was the largest we have seen in Europe as was the marble covered bathroom. Staff was friendly and efficient, and you cannot beat lounging by the rooftop pool. There is a grocery/drug store around the corner which was handy. The hotel was so relaxing to come home to after the wonderful chaos of Athens. We will definitely stay here on our next trip to Athens.

Tourist Athens is basically an small ancient town dropped into a sprawling modern city. Piraeus, the gateway to the Greek Islands is far away; the Saronic coast and Cape Souniam even further. The Marriott's 'tweener' location at 115 Syngrou splits the difference between Athens center and Piraeus, and is convenient for a traveller ambitious to see the whole of Attica; not just the area surrounding Syntagma Square and the Plaka. The hotel restaurants are pricey but the food is good. Room service is swift, the staff is polite and responsive, and will actually talk to you beyond the first sentence if you indicate interest. There's even a Starbuck's in the lobby. The rooftop bar-restaurant and swimming pool offers a clear view of the Partheon, doubly beautiful at night when the lights are turned on. I found it a good place to gather perspective and plot the next move. The area surrounding the hotel is filled with small, inexpensive tavernas, including one or two Italian and Chinese. The entrance to the Acropolis is a meandering 0.9KM up a through a pleasant non-tourist neighborhood. Walking through these streets I experienced more of how Athenians live in terms of street life, shops, and residences, and came away with a more indelible sense of a comfortable city at ease with itself, then the forced marches through the Plaka and Monastiriki areas with my fellow tourists. To be fair, I visited Athens in August when the line between a traveller and a refugee is blurred. Having been warned about Athens taxis I had an edge on when I entered my first several cabs; but in my 12 day stay I must've taken over thirty cabs and only had two disappointing experiences. The meter was 'broken' in one and flat rate charged; in the second the cabbie turned into a 'wild 'n crazy' tout and I had to refocus him on getting back to the hotel. You run into much worse in New York. It's time to lighten up on Athens cabbies. The Ledra Marriott was a good host, and helped make Athens a positive experience.