There are really two museums in this building, with separate entrances. The main museum has an interesting collection of items and paintings that show what it was like when it was a hospital. In addition it has some incredible art pieces, true masters of Flemish primitive style mostly of religious themes, plus a collection of silver reliquaries. This all housed in a spacious (cavernous?) building that adds a sense of scale.
For me, however, the highlight was the second museum in the building - the Picasso exhibit which is in a different part of the museum with a different entrance. It is a "special" exhibit which means that it's not covered by the museum pass. But it was well worth the extra fee. (You can find fliers about the exhibit that offer 1 Euro off the price) Many (supposedly 300 but I didn't count) of Picasso's relatively unknown works and drawings, plus a good collection of Miro plus Rodin, Chagall, Magritte and other impressionists. I spent most of my time in this exhibit and loved it. One aspect I particularly enjoyed was the posters along the way that provided the context of what was going on in Picasso's life at that time - very illuminating! They also described the friendships between Picasso and Miro and other artists. I enjoyed getting "the story" of the many phases of his art and life and seeing how they weave together. The Picasso exhibit (along with the other artists included in it) was definitely a highlight of Brugge for me!
This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.