The hotel is right along the Prinsengracht canal, and in the center of the city. From the airport, we just took the train to Centraal Station, and then take the trolley to right in front of the hotel. We were able to walk to the Anne Frank house, many of the popular museums, and to the start of a bike tour. The cons to the location is that this city does not go to sleep early, and it can be rather noisy from the street on a Saturday evening if you plan on going to bed early. You also can hear the occasional ringing of the tram bell.
We stayed in the Penthouse Suite which is VERY spacious and offered a larger bed, which I discovered is hard to come by in Amsterdam. The view is fantastic from the suite as it had huge pane glass windows that overlooked the city. However, to get up to the penthouse it required navigating up a very narrow, steep spiral stair case from the elevator. It’s wasn’t took much of an issue for my wife and I who are young and fit. However, and elderly or infirmed individual would have issues with it. Carrying our luggage into the room took a real physical effort. Also, the elevator was out of order when we checked in. The staff stored our luggage in bag check until it was repaired later that afternoon.