Of the hotels I stayed in on my 18 day trip during September and October 2012, this one was the most pleasant. I had a miniscule single room, but with all the very best and new fittings one could ask for from a five-star hotel. The breakfast was excellent without fail, the advice from the staff top-notch (they were more than helpful) and they were standing ready with my coffee (as I like it - or tea if I chose) on the house whenever I returned tired form a sightseeing trip. At first I was sceptical as someone mentioned that this is not in the trendiest part of Amsterdam (Amsterdam-West), but I never felt I was slumming. On the contrary - Amsterdam is a great place - I certainly noticed no slums or strange creatures lurking around or felt unsafe.
Tram service is easy once you get a good map - can't wait for my next trip and I will certainly stay in Hotel Larende again. P/s - use the shuttle service to and from the airport. Its a breeze and worth the 16 EURO one way.