So I was at the San Ranieri for one week. The hotel is located outside Pisa center, however the busses run frequently, and takes 10-15 min - So that is not a problem.
The hotel is very aesthetically nice, very clean lines and it really looks like at top modern hotel.
In my opinion there is a issue tho - This is not a holliday hotel. The San Ranieri is clearly more suited for conferences and work related seminars and not so much a relax hotel. The reason for this is missing facilities as swimming pool, staffed bar, and other facilities you might wish for.
Lack of Facilities as no pool etc is no problem ofcourse, as you are aware of this, however i found the unstaffed bar. (we had to run around chasing staff whenever we needed coffe, drinks and others.)
We only had one dinner at the hotel. This for two reasons; Our first experience eating at the hotel was not convincing, and there a reeeaally good and cosy restaurant 50m down the street, witch is awsome.