Dorsoduro is probably the best area in Venice. Close to the center but away from the crowd.
We had a very good stay at Palazzo Guardi.
It is composed by two buildings one minute away from each other.
Our room was at the annex with a nice view over the small canal.
Breakfast ok, very clean, good service and helpful staff (thanks again to help me to get back our lost luggage)
We will return there for sure.
A couple of suggestions:
ask the hotel to send you by email directions as it may be difficult to find it without them.
If you book this place directly through its official web site or by email it is cheaper than other third part web sites.