I had passed by the Papadopoli before on a visit to Venice so knew how close it was to the Piazzale Roma (think about this when you need to carry luggage). Although I had booked a single room (as I was travelling solo this time) I was given a very pleasant double with a queen-size bed. The staff were very friendly and the breakfasts excellent.
This is certainly a place that I would consider revisiting. Be aware that repair work is underway on the exterior of the hotel facing the Rio dei Tolentini that is due to continue for a few months into early 2013. This did not affect me.