I chose this hotel because of favorable reviews by others on Tripadvisor.com. I was glad I did. Location wise, this hotel is located in a Venetian neighborhood so, it's quiet and peaceful. There aren't any tourist crowds walking around and, there is a nice small park nearby with benches where you can sit and read if you wish or watch some of the kids brush up on their football skills (soccer to us folks from the U.S.). At the same time, it's easy to get to the prime sightseeing sites from the hotel. Take the waterbus and you can be at the Piazza San Marco in 10 minutes tops. I wouldn't advise walking to the piazza as you might need a map (though the hotel will be glad to provide you a free one if you need it). Also, I've heard it can take 30 minutes or more to walk from the hotel to the piazza. The waterbus is a lot easier and, it isn't that expensive in my opinion.
Concerning the hotel itself, my room was very modern, spacious and spotlessly clean. The free WiFi worked great. Hotel staff were very helpful. The breakfast buffet was very good. I did find the hotel a little difficult to find. I thought since it is within walking distance of the waterbus stop, it would be easy to find. It wasn't. The hotel does try to help in that way having a sign pointing the way to the hotel unfortunately, they put the sign before the sidewalk forks and, unless you have directions, you're left wondering which way to go. Tip: go right, follow the sidewalk till it ends, look for the street sign Calle Buccari on the building ahead of you (to the left of this building, you should see some chairs for a possible small neighborhood restaurant), follow that street/alleyway and you'll eventually see the entrance to the hotel on your right.
Getting to the hotel from the airport. You have 2 options. You can take a water taxi which is very expensive as I understand it or you can save some money but deal with a little bit of hassle. There is a shuttle service called Alilaguna which runs from the airport pier to the Lido island (where the casino is), you get off there and take the waterbus across the canal to the Sant Elena stop.
For those who are going to do a cruise out of Venice (like I did), the Alilaguna (blue line I think) shuttle will eventually take you all the way to the cruise ship terminal stop during the cruising season which ends in late November (I was on the last Royal Caribbean cruise out of Venice for the 2012 season). The waterbus as far as I know doesn't. If you want to use the waterbus, you have to take it to P le Roma, then use a tram which cost 1 or 2 Euros. I forget the exact amount. From the tram station, you would walk over to the cruise ship terminal. Venice has a very good cruise ship terminal.
Weather wise, I went in November and, it was chilly and wet. If you go then take a raincoat and wear a sweater underneath.
Another tip: if you think you're going to ride the waterbus a LOT, you can purchase tickets for various time periods which will allow you to ride the waterbus as much as you want for that time period. I think you can do the same for the Alilaguna shuttle.
This review is the subjective opinion of a TripAdvisor member and not of TripAdvisor LLC.