For anyone looking for a great hotel in Milan that is 4 stars I would highly recommend this hotel. The room rates here is reasonable and for what you get it is incredibly worth it. Compared to many other hotels in Milan that are rated 4 stars (NH Milano Touring, Michelangelo Hotel, and Best Western Ascot) this is by far the best! I have stayed in all the other hotels mentioned so can compare them.
The rooms are nicely decorated and are in good condition. Amenities such as slippers are provided. The bathroom is a decent size. Some of the other hotels mentioned still have decor from the mid 1990s and the hair blow dryer in the bathroom are still the ones that have vacuum cleaner hoses.
The Uptown Hotel is about 15 minutes walk to the Duomo (Milan Cathedral) and the main shopping area (Via Montenapoleone). The hotel is located in a residential area so the rooms are quiet. Nearby the hotel there is a supermarket. Taxi fare from Milan main train station to Uptown Hotel is about Euro 10. Nearby the hotel is the metro. So if you don't want to walk to the Duomo or Montenapoleone, it is just a couple of stops away on the metro.
The front desk staff were exceptionally helpful and friendly.