Traveling in Europe comes with some challenges when you have a large family (we have three children). We typically try to find a holiday rental or an Agriturismo but in Milan (within the city center) there aren't many options so a Hotel is typically the best option. Without a doubt, Hotel Spadari is the best option in Milan. The staff are friendly, the rooms are charming, and the service is unlike anything I have experienced in a hotel in Europe. Drinks in the minibar (the non alcoholic options) are free as is breakfast and internet access. The breakfast is more than the typical continental breakfast and also includes freshly squeezed orange juice, eggs and bacon made to order (or ham) and nice selection of pastries, cereals and yogurts.
The hotel is located near Duomo and within walking distance to the Quadrilatero della Moda and Sforzesco Castle. Next door to Hotel Spadari is a gourmet grocery store, Peck, where you can find a great selection of fine Italian wine, cheese, pasta and much more - everything you need for a picnic. There is a 5 Euro charge to drive into the city center but getting to the hotel by car isn't a problem. You simply park your car in front of the hotel and the hotel staff will take care of parking for you. There is a 35 Euro fee per night for parking but the hotel is easily accessible via train/subway.
Without a doubt, my family and I will be back.