The best thing about this hotel is it's location - really close to the Vatican and a short walk to the Metro. There are also some excellent pizzerias nearby, which are packed out with locals.
Downside is the banging door if you are in a room at the front of the house and a shortage of pastries if you get to breakfast too late.
However, we would stay here again.

We stayed at the Vatican Garden Inn for a few days while in Rome. The room was charming, in a good location, with a balcony overlooking a small street. The bathrooms, however were quite small and in need of repair. Our shower head shot water all over the bathroom and when we called maintenance to fix it, they simply loosened a bolt in the shower head, fixing the uncontrollable spray, but providing zero water pressure. We also had a problem with the hair dryer falling off of the wall, and unfortunately our room had no back-up hair dryer. Although they advertise Wi-Fi, we were unable to pick up a connection in the room. The only area that I found connection was the check-in/breakfast area, a few blocks away from our room. One evening we came home to an obnoxious alarm going off. When we called the front desk, no one was there, as they had left for the evening, so we were forced to deal with a loud alarm until it shut itself off a few hours later. There was 1 staff member that we saw in the 3 days that we stayed at the Vatican Gardens Inn. I felt quite bad for him as he tried his best to accommodate us, but 1 person isn't capable of tending to new guests, checking out guests that are leaving, preparing breakfast each day, tending to the grounds, and helping people with room problems. Overall, I wouldn't recommend staying at the Vatican Gardens Inn unless you're only planning on staying there to sleep and not shower.

The decor & the rooms are very nice, and the location is very close to the Vatican. We strolled from here through Rome, but I guess it is long even though the walk is usually described as 30-40 min to Historical Rome. but, one can always use the metro with the Roma Pass and it makes movement very easy. Their breakfast was really good and filling. The front office staff spoke excellent English.

The breakfast is continental not American as stated no guest lounge, breakfast is served in the garden in a gazzebo with plastic sides not good for the winter. Our room was clean but small had to walk side way to get passed bottom of bed, bathroom very small shower falling of wall hair drier broken ( spare hair drier in draw ) and in need of deep clean.