This is a very small B&B and one that is a bit dated. There's no kitchen or common areas and a musty smell remains in the hallway and in the room. The room was very clean (esp) the bathroom, but wasn't a room that you could really get comfortable in. The location will require that you take the train to most of the sights (except for the Vatican) which wasn't a problem, but it might be worth the extra money to stay in a place that is more centrally located (e.g., near the Spanish steps). The staff was ok, but it was an everchanging case of people and sometimes no one was around when we needed assistance. I would recommend it only if you are on a budget which we were.

We totally loved our stay at the Residenza Vaticana in March 2007. Booking was through Romeby.com, and although it was a bit pricey for our personal budget ($120), I was extremely satisfied. Upon our arrival, we learned the owner/manager had generously upgraded our accommodations, transferring us to their newly opened rooms just a few blocks away. The rooms are on the 3rd floor of a very well maintained and secure building. The entire floor occupied by the inn was very plush and well decorated. Everything is new and amenities are modern. Customer service (i.e. reception, information desk, house keeping, breakfast service, etc.) was great, the staff was always eager to please. Location was very convenient to local shops, the Vatican area and railway system. The inn is situated in a calm neighborhood of shops and buildings, less busy compared to West of the Tevere. During our stay we had to pay cash because the manager was still arranging credit card services, as this truly was a newly opened facility. I would highly recommend this inn for its location, comfort, luxurious amenities (-using European standards) and kind management & working staff..

This was a perfect location for us. The B&B is in a condo building so it feels private. No big signs of hotel or anything. It is in a residential area.
the service was fine, except the reception guy gave us the wrong info on the vatican museum, causing us to miss our visit on the free day. We had breakfast in our rooms everyday (part of the deal) and that was great. we also loved the italian music channel on tv. the room was wonderful and designed to make the most efficient use of its space.
One tip, do not eat at nearby Piazza Cavour. all the bars/restaurants in that area have bad service, very expensive for the low quality food, hidden cover charges, beverage prices not listed (and ridiculously expensive). we stayed in this area for 5 days and experienced (or witnessed) the same problems at 8 different places there.

We spent a full week at the Residenza and had a wonderful time. The rooms was impeccably clean and the service outstanding. The room is small but that is the norm for Rome. Besides, we were hardly ever in the room as our intent was to see the city. The Residenza provides a private oasis on a quiet street. The location is actually ideal as it is within easy walking distance of the Vatican, Piazza Navona, and it is very close to the metro which can get you virtually anywhere you need to go.