The four star Hotel Alimandi Vaticano is one of three hotels in Rome run by the Alimandi family. Opened in 2002, it is located right across the street from the Vatican Museum. It's not really near any other of the main tourist attractions, but there are two metro stations a couple blocks away, Cipro "Musei vaticani" and Ottaviano "San Pietro".
Each of the front desk staff were truly helpful and willing to give suggestions and directions. When we checked in, they offered to help with our bags and asked if we needed any suggestions for anything. We checked in around 2pm, and the girl told us that was a really good time to go to the Vatican Museum since there was a barely any line, so we went. Every morning there were lines all the way around the block. They also gave as their card and told us to call them if we needed anything at all while we were out.
The room was average size and the bathroom was fairly big. The rooms have a mini bar, safe, free DSL internet, direct dial phone and a desk. One major problem we had was that the rooms were not sound proof at all, and the hallways were not carpeted. We were unfortunately on the same floor as a family (or two families traveling together) that had at least three other rooms on the floor and just had to walk (loudly!) from room to room, talking (loudly!) at all hours of early morning and as late as midnight! I know this is not the fault of the hotel (and I did ask these people numerous times to quiet down, and they didn't), but if you are light sleeper I strongly suggest earplugs.
There was a huge selection at breakfast. It was the biggest one I saw anywhere in Italy. There was all of the traditional pastries, fruit, meat and cheeses and bread, but then there was also bacon and eggs, sausages, and even scalloped potatoes. The breakfast staff were also pleasant.
The elevator is big by European standards, but there are not too many stairs between floors.
We paid 200 Euro a night.
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