This is a great little hotel in the heart of Rome. Literally 4 blocks from Metro stop Ottaviano, and just 1 block from the Vatican! We had their best suite, which was on the corner of the building and had a view of the Vatican. While I had heard so many great things about Angelo, I never saw him during our 4 night stay, but the staff that was there was very friendly. All in all a great deal!

The positive - lovely and charming rooms; friendly manager/nice staff; great location-very close to metro, taxi station, Vatican, good ristorantes/pizzerias/cafes nearby; private location
If you are looking for a place to stay for reasons listed above, i would probably recommend. This was actually my 2nd stay here and did not experience some of the hiccups listed below during the first visit.
However - as a heads up/fair warning - this B&B is located in the 4th floor of a residential apartment building, the elevator is an old fashioned and typically small european cable lift (got stuck once mid-floor going up but quickly received help from nice local residents and were told to push #5 down for a few seconds to continue, funny in hindsight but not at the time!). We opted to take the spiral staircase instead thereafter, being fairly fit we didn't mind taking the stairs (not recommended for the disabled). If you need to check out very early in the a.m., be sure to make arrangements/check out the night before - as this a B&B, no 24/7 front desk but you are given a set of keys to the building to come and go. However the manager, Angelo, very friendly and accomodating is reachable via cell phone for your needs. This happened to us one morning had to leave before 8am-no one there and didn't get our breakfast (which is a delightful breakfast by the way). Called Angelo and he arrived quickly.
When traveling to Europe I personally prefer to stay at places like these as opposed to typical chain American-type hotels abroad.
The rooms were charming and clean, very comfortable bed. There is so much to see and do in Rome, you will not be spending much time at the hotel.
Everything considered I would recommend...

We booked this hotel almost 8 months ahead, based on some very favorable reviews on Trip Advisor. I even confirmed our reservation via email a week or so ahead and was assured all was in order. We arrived at the door after taking the metro across town at the expected time, and were then informed there was a "problem with the bathroom" in the room we reserved & it could not be fixed until at least the following day. The manager/owner assured us that he would take us to a much better location which was "far superior and give us that room for the same amount we were to pay at Ottaviano." He took us by taxi to another small suite near Trevi fountain, which was in fact a very central location, and not wanting to pack up and move again, we remained there for the duration of our stay. The central location was good, but we had to relearn the area with regard to metro lines etc.The room was quite functional with excellent bed, air, bath, TV and other amenities. However, it was located on a side alley way and was dark due to other buildings abuting it. (The large sunlit windows in the photos of the Ottaviano hotel were what attracted us there in the first place.)
The bottom line is this: There have been far too many similar instances noted in these reviews to believe it is an isolated occurence. Unless the Suites di Via Ottaviano are in much poorer condition that they appear from the photos, it is unlikely there are such frequent problems with bathrooms. Perhaps all the switches are due to overbooking. Since there were positive aspects to the alternate room we were given, I suggest that If you book this hotel, do so knowing that you may be switched at the last minute to an entirely different location due to "problems with the rooms". Since I did not get in the building of Le Suites di Via Ottaviano, I can't comment on the property other than perhaps the booking practices. The Asian man who brought us breakfast each morning was nice and helpful as could be and overall, it was a very good value for Rome.

We booked the 4poster room for 4 nights. The hotel states that should you arrive no later than 9pm at night and if so you should contact them in advance. I did just that and received confirmation from Angelo the hotel manager. We arrived at 22:00 as stated in our email to find no-one answering. It is more like an apartment than a hotel (i.e. no Hotel front/reception etc..) We then called the mobile number provided but there was no answer. In the end we wandered the streets of rome around 22:30 until we found a hotel nearby. I then tried calling early in the morning. Angelo eventually answered, apologised and said firstly he had not received the email. Then when i confirmed he had, he then said he mixed his diary up!!! Apart from this the hotel was pretty much what we expected- good location & nice room; but it was not the start we were looking for. If you stay here, you'll probably be best taking Angelo up on his offer to ferry you from the airport for 45euros than chancing it!!