We took a flight to Leonardo da Vinci–Fiumicino Airport, hopped on the train to the Termini station (14 euro a person) then took a metro (subway) to the Colosseum (2 stops), the hotel is not very far from there but I suggest you take a taxi since you will have luggage. It's 10 Euro to the hotel. Once you walk out of the station, make a right and about 50 feet from there, you will see the line of taxis.
Now to the hotel part. When you look at it from the outside, it looks like a regular little hotel, nothing fancy. You walk in and at first, you will be like "where's the reception area" because it is not your normal lobby room. There are 2 little glass desks, one on each side with a receptionist sitting there on a Acer laptop and there are 2 chairs on the other side. At first I thought it was kind of odd and not very professional since I am used to the regular hotel when they give you a map and keys and send you on your way... Not this place. We were greeted by a young lady named Alina. She not only explained the significant pieces of history around the immediate area, she recommended places to eat, called and made 4 different reservations for us at different places and pinpointed every single place you would want to go. If she did not know for sure the exact location, she hopped on her computer and looked it up. It was incredible customer service!
Now to the room. The room was nice and decently large. Mini Bar is stocked up pretty nicely. There are no restaurants or anything in the immediate area so you do not have to worry about people eating outside being loud or anything. The eating establishments are close enough that you can get there with a quick 10 minute walk. The hotel is also right between 2 hop on-hop off stops so if you plan on doing that, it is very convenient. There is a restaurant upstairs on the top floor with a nice view. We didnt eat there but we checked it out and had a drink. I saw a drink because the prices were a little steep. 12.50 euro for a cocktail. It was cheaper at the Hard Rock. I cannot comment on parking because we did not drive here but I would recommend taking public transportation because they drive a little crazy in Rome.
There is a sauna and a pretty respectable weight room. I was pretty amazed with the weight room. There are robes and slippers in the rooms for you. Breakfast was decent. Eggs, bacon, sausage, cereal, meats, cheeses, coffee, juice, breads and it was buffet style. Breakfast is served until 1030 so you dont have to wake up too early if you want to eat. Wifi in the rooms was pretty decent. I can't complain.

Sorry if this was kinda long. I try to give as much info as possible. I would highly recommend this hotel.

Big thumbs up to Alina!

My husband surprised me with a w/e in Rome for my 50th birthday and chose this hotel for it's location and reviews. I wasn't disappointed.

The hotel is closely situated to the Trastevere district where we had 2 lovely meals at 'normal' prices. It is also close to the Colisseum and Roman Forum, which was a 10 minute stroll. We also walked to the Vatican - along the river until you reach the bridge with the sculptures, took about 30mins and that was with taking photos along the way!.

Our room unfortunately overlooked a side street (didnt get the nice view that hubby requested) but it was quiet & well equipped. If you are charging batteries etc overnight please note that the sockets appear to go off when you turn off the lights - it took us a while to realise why things werent charging overnight!

Breakfast was very nice, good variety and never too busy. We ventured up to the roof top bar on one occasion for a drink - lovely views from up there.

The staff are very friendly and helped us arrange our return transportation to the airport aswell as advising on restaurants in the area.

We both had a fantastic w/e - hoping for a return visit very soon!

This was a beautiful hotel in a fantastic location. Both centrally and the views around. The staff speak fluent English and were extremely helpful from start to finish. They even made some reservations for me at local restaurants as I knew it would be busy during Valentines. Would certainly recommend it and if I return to Rome, I would stay here again. Thank you!

Great staff, luxurious rooms, walking distance to all the main sites a superb base to explore Rome from. We stayed in February for three nights, the only fault we could find was that unless you like the news channels there was very little on the TV in English. I guess that was a hint to go and explore. Enjoy this cracking Hotel.