My family and I stayed here in May 2008 for 5 nights and had a very pleasant time.The staff were polite,friendly and helpful.The hotel is very pretty with loads of character, centrally located and most of the popular sites are within walking distance.Even though it's not advertised on their website they will arrange a pick up from the airport (3 of us with luggage cost about €50 and is well worth it particularly if you are new to Rome and don't fancy schlepping loads of luggage over cobbles.) The hotel is situated in a cobblestoned laneway off the Piazza Farnese which looks vaguely threatening when you arrive at night but is just plain charming when you get your bearings the following morning.
We would certainly stay there again which is always the best recommendation

We recently stayed here... while it wasn't a hotel i would write home about, it was in a pretty good location close to the major sites and the staff was helpful.

Having heard that European hotel rooms were generally smaller than US hotel rooms, I wasn't surprised to see how small the room that we had was. Residenza Farnese, however, apparently has different sized rooms for relatively the same price. And the bathroom sizes and configurations also differ from room to room. One bathroom had a toilet that faced a wall which was about 2 feet away. The rooms are not soundproof so there will be street noise, especially from workers in the nearby businesses. Breakfast is served at about 7am consisting of hard rolls, cheese, "deli" meats, fruits, coffee, tea or water. And a small bar, from which you can get a glass of wine in the early evening.

Most of the staff was friendly and helpful. There is one woman (the owner?) who always seemed sour-faced and not very helpful at all, but for the most part, the rest of the staff really tried to understand our desires and accomodate them. They even politely smiled at our attempts to speak Italian to them.

The hotel is within walking distance to many of Rome's main sights. Campo de Fiori is a block away. Buy some fruit there to take on your day's journeys and in the evenings, it becomes a gathering place for the young and young at heart. Piazza Navona is a 5-10 minute walk from the hotel. I even walked to Castel d'Angelo and the Vatican in about 20 minutes. Many great restaurants and cafes are also situated close to the hotel.

Just got back from 3 nights here with my girlfriend. Absolutely fantastic hotel, full of character, tastefully decorated. Spotlessly clean. Amazing location on a lovely side street just of piazza Farnese and 30 seconds from Campo de fiori. Within easy walking distance of every sight in Rome, including the Vatican. Very well located for the Trastevere, just a short stroll over the Tiber. I do not think the location could be bettered.

We asked for a room overlooking the Palazzo Farnese, which we got. Fantastic view of the gardens of the Palazzo. The size of the room was more than adequate, generous double bed, writing desk, mini bar, good sized wardrobe, nice bathroom, LCD TV. Room was quite, the side street is not a busy one. This was a standard double room.

Reception area is lovely when you walk in, as is the breakfast room and the food to go with it. Lovely fresh pastries / fruit / meats / cheese / bread / jam / cereals / cake etc etc. Coffee also very good.

Staff were friendly and helpful. We arrived early, they took our our cases and gave us a map and quick intro to nearby sites to see until our room was ready. Cases were waiting in our room when we came back.

Would recommend this hotel to anyone. Very good value.