Stayed for 6 nights at the Lirico hotel, and can honestly say that I fell in love with the hotel (and Rome)... Location is flawless; not too far from Termini, but not too close to the busy bus terminus and main road... Though found the metro station at Piazza Republic to be better (which is also closer to hotel). Literally 1 minute away from the beautiful Via Nazzionale.
Best thing about the hotel is the reception staff (Tony, Emiliano, and Chan) who made our stay wonderful. If Tony asks you if you want a restaurant recommendation, say yes, believe me, he'll tell you about a great restaurant close by that we ended up going to nearly every day. Reception staff are also extremely helpful and nice to talk to. To get to the reception area there are some stairs, but if you're the type that loves travelling for a whole day around the city viewing different landmarks, then a few stairs wont tire you down.
The rooms are very clean, and surprisingly spacious. Bathroom was also really good and well stocked to nice towels, soaps, etc... Room had a really good A/C and nice big windows. offers a reasonably good buffet breakfast (boiled eggs, ham, yogurt, cheese, buns, pastries, fresh fruit, juices, cereal, milk, jams), breakfast room was on the small side, but always found a table...
Hotel offers a comfortable hotel transfer service from Fiumicino airport for 50 euros. Had found loads of hotels in Rome before choosing this one, and Lirico just seemed to be perfect compared to a lot of the other hotels in Rome, and it is. Would definitely recommend and if I had to go back to Rome, I'd love to stay there again.
Rome is also breath taking, a definite must-go at least once in a lifetime. Didn't experience any criminal activities what-so-ever. Would also recommend to anyone planning on going there to try and go either early summer (May, June) or end of Summer (September), since the weather was just right, and would be less crowded then in the middle of summer. Most helpful buses were no40 and 64 mainly.

Comfortable friendly hotel. Close to many attractions and short walk from station termini. Reception staff always willing to answer questions and offer advice. Ask for cappucino at breakfast if you enjoy good coffee. Hotel organised taxi to fuimicino airport for set price of 50 euros, may cost more on Sundays. Happy to recommend this hotel.

We spent 3 nights here. The rooms and bathrooms are very clean and the staff were extremely friendly and helpful and speak fantastic English! The hotel is in a great location, only a ten minute walk from the Colosseum and near lots of pizzerias and bars. There is a Metro station a few minutes walk up the road from which you can access all parts of the city.
They serve a continental breakfast including cereal (cornflakes & coco pops) and you can have as much as you like.
I would definitely recommend a stay here.

We travelled thru Europe this summer and booked alot of hotels thru trip advisor. Everything went very well. We were on the train and chose hotels near train stations. The Lirico was easy to find and everything we needed. Easy to get around Rome and the front desk always had someone on with advice, answers and tips. A great breakfast to start the day and safe area for our luggage on our last day as we had a morning tour and did not get back to hotel til mid afternoon. The smallest fo any rooms we stayed at, but still comfy for 3 people and very clean. We are defenitely going back to Rome for a longer stay(only 3 nights this time) and will look forward to staying here again.