Hi - we stayed at this hotel for 3 nights in May 2013. We were delighted by the large room (Room 47 - a triple room) and the south facing window so that the room got sun during the day. The staff were very professional, helpful and cheerful. For example, when ordering a taxi, they would always check it out before letting you board, as they wanted to make sure you were not being picked up by a rogue driver. We enjoyed breakfast on the rooftop terrace - good variety of food and very pleasant surroundings. Hotel was clean, and with good facilities.
We were lucky to have fine warm weather during our stay, so we walked to Trevi Fountain (about 350 metres easy walk) Pantheon (about 300 metres easy walk) and Colosseum (about 20 mins walk). We had dinner at the street restaurant on the street just a few metres along from the hotel's front door! Food was good value - nice but not too flash and at a good price - and we had good service.
If you are visiting the Colosseum - you can cut down the waiting time by buying your tickets at the entrance to the Roman Forum archeological area a couple of hundred metres away - just south of the Arch of Constantine (tickets are for entry to both and are valid for a day and a half - so you can purchase them the day before too if you wish!). Once you get into the Colosseum itself, save time by getting into the middle queue - the short one - and ask for an audio-guide (self tour)! You will waste less time in the queue as few do this, and then you can cruise around the place at your leisure.
If you are visiting the Vatican - we ordered a taxi at about 8.15am to get there early. Ask to go to the Vatican Museum (and Sistine Chapel) first, as you have to buy tickets there. You can then walk around to St Peter's square, where there is no entry fee - there is only a queue for security. You will waste less time in queues that way!