My daughter and I stayed at the NH Giustiniano a few weeks ago for eight days. the hotel is on a quiet side street within walking distance of the Vatican. it is well located with shopping and restaurants nearby and is about an 8 to 10 minute walk from the metro. The full breakfast is excellent .
we upgraded our room for 20 euros a night. It was well worth it for the larger room , minibar and included Internet. The room was a nice size and had the most comfortable bed i've slept on in Europe. It was immaculate but the highlight of the stay were the people at the front desk. They were most pleasant and helpful in every way. There are a few NH hotels in Rome..actually we thought we had reserved in a different location. It worked out very well and we were very satisfied with our stay.