Gran Hotel Domine is for me the best place to stay in Bilbao.
The hotel is luxurious, with modern design, comfortabe rooms with huge bathroom, nice breakfast. It is situated downtown, next to the guggenheim museum, so you eat your breakfast with this view.
The only minus I would find is a small delay in the check in procedure, probably because it happened to arrive many people in the same time. In the check out, there was no delay.
I overall strongly recommend this hotel for business as well as for tourism.
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