During our 4 night stay in Seville, we did not venture much beyond Santa Cruz (although there is much to see in Sevilla). Our first impression was during the cab ride from the train station to our hotel (Dona Maria). We were blown away when the cabbie turned from the boulevard onto the tiny streets of Santa Cruz. What an experience, including the Spanish DJ on the radio! It is labyrinthine but not so big that you would get lost. We were reminded about how many operas have been set in Seville, and there are plaques to tell you about them. Of course, lots of shops and restaurants. However, don't miss shopping on Calle Sierpes, a short distance away.
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