Stayed here during a work trip in October 2012. Location wise there is not much in the immediate surrounding area - it is very quiet in the evenings and especially during weekends. This means you can get quality sleep. Despite the quietness, it did not make feel the area unsafe. It is within walking distance to the centre and if you don't like walking, you have a lot of public transport options. The underground, the tram etc. Just go towards Messe. The little things that I noticed: Movenpick chocolates the housekeeping leaves on the bedside each day, and the rubber ducky in the bathroom/shower.
P.S. Internet is not free and there are no porters - you can find trolleys at the lobby.