The ambience at The Boston is something to write home about - welcoming, cozy, and warm. The staff are young, friendly and unfailingly polite. Our room was huge, very comfortable, and spotlessly clean. We didn't try the breakfast because we woke up very late every day, but we also felt that at 18 euro per person it was a bit much.
The hotel is situated out of the city center, but with good public transport connections. The S-Bahn stop is 5 minutes away, and there are also regular buses. The area felt safe at all times. There's a supermarket close by, with a good bakery which also offers excellent coffee.
Only one stop away on the S-Bahn is the very cool Sternschanze district, where you can eat and drink at very reasonable prices and meet interesting people.
All in all, The Boston comes highly recommended.