The hotel is centrally located and is close to Friedrichstrasse train stop. From Schoenefeld airport we took a train to Friedrichstrasse stop with a changeover in between (can't remember the name now). Total journey took us 45mins or so and from the train station it was hardly a 10mins walk.
The hotel is very close to all the main attractions in Berlin. We took a full day subway pass but only used it once, everything was at walking distance. There are good restaurants on Oranienburger Straße (10-15mins walk from the hotel).
The hotel room was really good, very spacious, well laid out and had a super comfy bed. We got a room facing the river and the view was really good. The bathroom was really spacious as well. Apparently hotels in Germany don't give free wi-fi, but since we signed up for their membership we got it for free. We also got 15Euros a day as a gift voucher to spend on room service because of our membership :-).
We didn't sign up for breakfast and we had to sign up for our full stay. However, we were leaving early so chose not to take breakfast.
Staff was very very helpful, even gave us complimentary champagne for our anniversary :-).
Overall this hotel was good value for money (we got a discounted rate though), very good location and would definitely be back if we ever visit Berlin again.