This is not a typical hotel style hotel but rather an apartment style where you can find a bathroom with a washing machine and a dryer, well equiped kitchen and a bedroom separate to the kitchen/dining/lounge area. This especially helps if one of the travellers is more jet-lagged than the other. The apartment is quite spacious. The bedroom is lovely. the bed is really comfortable. The service was great, very helpful staff. The swimming pool and spa were a real treat during winter as it's quite nice to be able to take layers of clothes after sightseeing all day and dip in and relax.
The hotel location is not the best as it's situated right next to Charite hospital in a very quiet area. Hardly any caffes and restaurants. Need to walk to Friedrich Strasse for those. The hotel is located about 15 minute walk from Unter den linden and Reichstag so not that far away. Berlin is a big, big city so no matter where you stay something is going to be far away from your hotel. There's a bus stop right outside the hotel. The good is that Hauptbahnhof train station (the main station in Berlin) is only a 10 minute walk away. If you're land at Tegel it's only about 17eur in a taxi so don't bother with trains of shuttle buses.
The only pickle we had with the hotel, which is nothing major, is the housekeeping. It was very random. Some things would be replaced when you didn't want it replaced (towels for example, when you hang them up they shouldn't replace them according to their sign yet sometimes they did and sometimes they didn't replace them) and some things that you wanted replaced (milk in the fridge) they wouldn't replace. Apart from that everything was perfect about this hotel and I would definitely go back.