My family and I stayed in two rooms for two nights each this hotel. The hotel was well managed, staff were friendly and helpful and the rooms were clean and comfortable. Despite the fact that we booked the rooms together and paid the same price, they were substantially different, however. One room was moderate sized with a long hallway leading to a large bathroom with a bathtub and hand shower. The other was small with a small bath with only a very small shower stall. So, be prepared for the fact that this is an old hotel and the rooms are not "cookie-cutter" as you find in most current US hotels.
The location of the hotel right on Place De L'Horloge was excellent. We spent two days thoroughly exploring the old city and historic areas and enjoyed our experience in Avignon tremendously. We had to park outside the wall and walk our suitcases into the hotel (not a great distance, but cobblestoned and uneven for most of the way). We chose not to take breakfast in the hotel (very expensive) because it was easily available in many local restaurants for one third the price and we enjoyed the adventure of finding a new place each morning.
One note: there were three small sets of stairs from the elevator to our room so this is not the best hotel choice for those with mobility issues.