We stayed in the Comfort Suites for 5 nights & found it to be an excellent choice. The neighbourhood is not as bad as some of the previous reviews make out. There was four in our party & we NEVER encountered any trouble or NEVER felt unsafe @ any stage during our stay. On the contary we walked from the hotel to the downtown area every day. There are a number of other hotels in the vicinity & surely if it was a bad area they would not have located there. The hotel is located at a busy intersection of Dundas St West & Jarvis & The Eaton Centre/Dundas Square is only a 5 min walk away. But enough of the perceived negatives of previous visitors & let me highlight the positives!
The hotel is itself is clean & modern with large rooms. There is an excellent buffet breakfast served until 10.30 each day. The pool is quite small but the spa bath is a good way to relax after a day's sightseeing/shopping. The walk to downtown can take 10-15mins but there is good public transport & taxi's are reasonable. The Toronto Film Festival was in full flow whilst we we in the city which created a nice buzz. Toronto is a really nice place to visit & I would recommend it & The Comfort Suites to everyone.

I had booked a King room online, and much to my delight we were upgraded to a Penthouse suite, same price. It was very spacious and clean, but it needs updating. The decor was pretty average. Staff at the desk were friendly. There was no indoor parking left, so we had to park at an outdoor lot across the street from the back of the hotel. It wasn't even on the property, yet they charge $16 a day.
We ate at Caseys, the onsite restaurant. Very good meal. It's true that it isn't the best area, but it is only a short 10 minute walk to Yonge St.
My overall impression: the price is right, the hotel is not terrible, but it is not a 4 star establishment. It could use a renovation. New carpets etc.
The hallways were spotless, as was the room. Lovely lobby. For those of you who are complaining about the 'drug deals' out on the street, well you can pay $400 a night at a 4 star place and see a drug deal as well. Downtown is downtown.

Upon arrival at the comfort suites, we saw numerous drug activites--before we even got out of the car, we had a beggar knocking on the window. The room stunk and had burn holes in the sheets--immediately we booked another hotel. The conceirge there told us that the Comfort Suties is located in one of Toronto's few sleazy neighborhoods. TERRIBLE HOTEL

Stayed here with my partner for a week in november, we were very pleased at this hotel the room was nice plenty of space for the two of us, it had everything that we needed, large king size bed, fidge, microwave, clean bathroom. We made use of the pool most days and the hot tub which was very relaxing after walking around toronto all day. The hotel staff were very friendly and helpful, we would stay here again and recomend this hotel.