The Best Western Downtown is a great casual stay for the money.
We have booked here a few times and always had a clean, well appointed room with no hassles. I would recommend this hotel if you want a no-frills, clean & stress-free stay. Location is relatively central as well.

I stayed at the Best Western Downtown Vancouver for a couple of nights in May 08, and was very impressed. The hotel is modern, comfortable, and clean. The hotel staff were helpful and welcoming. It's in a good downtown location at a reasonable price. While there's not much directly around the hotel, it's a short walk to Robson St, and close to Granville Island.

Perhaps my only problem was with the chain restaurant attached to the hotel, where the staff were rude and the service was slow (waiting over an hour for breakfast is just not acceptable). But if you avoid them you should have a good stay.

I highly recommend this hotel if you are visiting Vancouver and want something close to the city centre. I am planing a trip to there next year and intend to go back to the Best Western Downtown.

The Best Western in Downtown is really a good deal! We stayed there 2 nights and it was fabulous. The hotel itsself is definitely great. Wonderful view from the roof, while you work out in the fitnessroom, play table-tennis or relax in the jacuzzi.
The rooms are really nice, large and clean and absolutely calm (really amazing)! Beds are comfortable.
The area is not as bad as it is sometimes described here. It is not unsafer than the rest of Vancouver! There always people on Grainville Street (This is the ''worst'' street), the 7eleven is open 24hours and there is a police station, just 50m down Grainville Street from the hotel. So it should be fine! A lot of other hotels are on Grainville Street by the way (Ramada, another BW, Holiday Inn Suites is in the street next to Grainville Street,...)
The bad parts of Vancouver are Surrey and definitely Hastings Street, which is between Gastown and Chinatown. Just get sure you don't walk around there in the dark! But these parts are far away from this Best Western!

I can really recommand this hotel, but only 4 of 5 stars, cause parking is not for free and there is no breakfast included!

My husband and I stayed for 5 days and had a lovely room with everything you could wish for,even an uberella which was useful as it rained for the first 3 days. The area around the hotel was not very nice,a lot of homeless people,although they were harmless.
We had a 4 day trip to Vancouver island and visiting relatives and returned to Best Western on 10th October staying for 2 nights before taking the train to the Rockies, however the room we were given was very small and we did not have half of the things we had when we stayed for 5 nights.