I read about this hotel on tripadvisor and thought it would be good value. No website, just a phone so I called and used my booked a room for 300 peso/night, about $24 tax included. Not sure if there was tax, when I checked in all I did was give the young girl cleaning the rooms 600 pesos for two nights. Should have asked for a receipt to prove I paid for 2 nights but there was no problem.

An easy walk from the pier, maybe 2 blocks at most. Central location so quick walk to most places, maybe 4 blocks to the beach. Lots of small shops and restaurants all over the place. I recommend the cocina economicas, small restaurants where the locals eat. Had some great tasty meals for about 60 pesos. Small laundry about a block away, did my laundry in two hours for 60 pesos. Liquor store right across the street, any time I got thirsty I stopped by and bought a beer for 13 pesos.

Took a room on the 3rd floor. No air conditioning, just a ceiling fan. Daytime temps were around 28 celcius so hot evenings weren't a problem. Although the room was clean it was a little dated with faded paint and paint chips in the wall. Electrical switches and outlets were about 50 years old. Shower head was rusted, there was warm water, mirror was faded and tough to see my reflection when shaving. No safe in the room. Relatively quiet at night although you could still hear street noise. Mornings were noisy, I think another poster mentioned the rooster, sure enough it started crowing at sunrise, luckily I turned in early both nights so getting up early wasn't a problem. Didn't see any bugs in the room and no mosquitoes despite no glass in the windows, just wooden louvres.

Anyway, I recommend this hotel for the value and the fact that I enjoy basic accommodations as long as they are clean.

I stayed at Hotel Osorio for 4 nights, it is situated very close in walking distance to the ferry harbor and also to the main street of Isla Mujeres.

There are two types of rooms available, with or without AC. As the hotel was almost fully booked and I didn't place a reservation beforehand the only choice I got was a double room without AC but with a ceiling fan, which was 300 Pesos per night. The room was situated on the floor above the reception. It is very spacious, not very clean but not dirty either at an average hostel level I would say. The beds and linen were clean, the mattresses have seen better days, no real comfort here.

As the room had no real glass windows and not a mosquito net on everyone of them, I've been attacked by some of them during night. The hotel is close to the main street so you might hear some noise from (most likely) drunken people passing by. One night I was seriously bothered by a group of guests from the hotel who came home around 5 o'clock in the morning and kept partying in front of their rooms. The following nights there were no disturbances whatsoever..

Overall I think it is a good budget place to stay, especially for backpackers. If you plan to be outside most of the time and don't expect a cozy hotel but more of a hostel it will be alright!

Once we visited Isla and decided to move from Cancun, I read reviews and decided to check out Osorio. We were blown away by the price - 300 pesos (about $25 US right now) for a very basic room for 2 with no A/C. They did offer rooms with A/C, fridge, & tv for 500 pesos (about $42), but we were planning to hang out mostly at the beach and in town, so we opted for the budget route. We got exactly that - very basic, but clean, with friendly staff. Great location right in the middle of town, close to beach, ferry, restaurants, etc. I slept fine at night, but we did wake up early in the mornings thanks to some nearby roosters. Would come back if I wanted a very good deal!

We traveled with a group of 10 adults, ages 22-72, to Isla Mujeres for a week starting Dec 31 2010. The Osorio has a big wonderful roof-top terrace where we spent cocktail hour every evening. There's plenty of room to play games, hang up the clothesline, use the internet from the restaurant across the street. The rooms are clean, not fancy, but who wants to spend vacation watching TV in an air-conditioned room? The hotel is located 2 blocks from the ferry, about 3 blocks from the North Beach & 2 blocks from town square with nightly basketball games. It's hard to make a real reservation (we did have a Spanish-speaking friend call since our group was big). Rooms were 300 pesos per night, 500 pesos for AC/TV/mini-fridge room & we were there in the high season.