Nestled up in the hills above the city of Esteli is the Eco-Posada El Tisey.
I have stayed at El Tisey both as a tourist and to conduct rural get-aways with street kids.
It really is a lovely relaxing place to spend a couple of nights. Lots of lush greenery from the trees, a nice breeze in the air, good accommodation and nourishing food.
From the Eco-Posada you can take a short hike up to the 'mirador' to take in a gorgeous view over Esteli.
The Eco-Posada is also in-reach of the waterfall 'El Salto Estanzuela' which makes for a great spot to go for a swim.
The only major drawback is the journey. Without your own transport (and ideally a 4x4) it is somewhat tricky to get there. The first time I went to El Tisey I hitch-hiked from Esteli. It was a bit tiring, but for the adventurous minded easily done. There are also two buses which run from Esteli to El Tisey.