We stayed 8 nights at the Intercontinental in Tokyo Bay. I am a big fan of the IHG experience and also a priority club member so staying here was a no brainer. Definitely pricier if you're looking for an economical option but worth the cost and also a lot more cheaper than the Intercontinental in Akasaka.
It is very conveniently located near the Takeshiba Station - you literally take a right turn from the hotel and there it is. Also, Hammamutsocho Station is a 15 min leisurely walk (or 8 mins if you're a fast walker) - very well connected.
You should definitely eat a couple meals in the hotel if you like - the restaurant on the 3rd floor has an amazing buffet and its coconut icecream is to die for. Also, we ordered the smoked salmon for dinner once and it was very good.
The staff is very friendly, there's a 24 hour taxi queue at the hotel lobby and there's a limousine bus service to Narita Airport. I recommend staying here even if you're in Tokyo for a business trip!