Well, if money is no object, you might want to consider the Marquesa. Or the Garden Hotel. Both look like top-notch lush luxury properties to me, but I have not stayed at either because I cannot justify the cost. A step down, but very comfortable is the Key West Harbor Inn. Over and above the comfort factor here is the location: literally steps away from the waterfront. We stayed here one year and liked it and have recommended it several times. We have also recommended Marerro's Guest Mansion, which is also in a good location, close but not too close to Duval. It is also haunted. Papa���s Hideaway is a tiny, off the beaten path place which is perfect if you really want quiet along with your Jacuzzi. Finally, consider Courtney���s Place which is somewhat larger and a little funky. Good luck.