Are you going to have a car while here? The Embassy Suites in El Segundo is a good choice among the airport hotels. Having said that, unless you are only here for one night and have an early morning flight, the airport hotels in general are not good choices - the airport is not too central and there's not a lot of dining options or walking around at night things to do. If you can share your per night hotel budget with us we might be able to recommend a better located hotel for you.
Starline will pick you up from this hotel and take you to their main depot in Hollywood for the Hop-On/Hop-Off tour - one of the tour loops (there are four separate routes/buses, you can take as many as you like) goes to Rodeo Drive.
Otherwise, reaching Rodeo on public transportation from that hotel will involve three buses and take a couple of hours. Its about a 15 mile drive if you'll have a car.