February is usually a great month weather wise. It can be cold (30's, occasional snow), but most often days are sunny and in the 50's, You'll be able to tell better once you are closer to the date. Jerome is a year around destination, and I'd say 97% of the shops are open at any one time. We have great history--3 very different museums covering mining and the history of the town, and a do-it-yourself historical walking tour with map. Some very nice local galleries featuring local and well curated selections of arts and crafts. No brewpubs but multiple wine-tasting rooms and a couple of bars with history and local color. Jerome is a nice day trip from Glendale and can easily be combined with a scenic drive coming and going, visits to nearby Native American ruins like Montezuma Castle and Tuzigoot.
It's about 2 hours each way with no stops from Glendale if you were doing a same-day trip.
By the time you take a tour of the Douglas Mansion State Historic Park in Jerome, browse a few shops/galleries, do a wine tasting and have lunch, you can fill much of the day. We have several historic hotels and B&Bs if you want to stay the night (and do more wine tasting).
Edited: 6:23 pm, September 04, 2013