Hi MSfreespirit from a sunny and celebrating Greek Easter Athens!
Nikis Rd is a road located very near Sindagma Sq. which is the central square of Athens, with many transport connections. Nikis is a small road which is not accepting so much traffic. Although i am not familiar with this hotel, the location is a nice and convenient one, and safe for sure. I 'll try to check just outside views of the hotel to give you a short description tomorrow. Although proposition of MSfreespirit is worth to check for, since she has made an extended survey several days ago.
As for the programme, is starting to get better now. 5 days in Athens are enough to have a really good and extensive view. 4 days can do the same. It depends on which your other destinations are going to be.
Let's start with Athens. In brief words, what you "have" to visit, since you are interested in antiquities, is:
- Acropolis and surrounding arcaelogical sites, all conveniently located in generally the same area, walkable in a day or two.
- Museums: Superb museums like the National Arcaelogical Museum with ancient greek and classical antiquities from 9th to 3rd BC centuries, the Byzantine museum with antiquities from 6th to 14th AD centuries, and of course Goulandri Museum of Cycladic art with preclassical antiquities dating from 5.000 to 3.500 BC. Also really good reviews exist for two newly built museums. One is the Jewish museum and the other is Museum of Islamic Art, both giving some image of adjacent spectacular civilizations. You can visit all of them on two days.
- General sightseeing: Plaka area, Anafiotika, Psirri area. Leisure and mostly pedestrian's areas with traditional housing, to give you some rest and food - cofee time.
4 days are enough for these, but first day will also be needed for some rest and "get in touch" walking or reccuperating from jetlag.
As for your other destinations, since you are not interested in the swimming and water part, but in the antiquities part, most important destinations are:
- Olympia in Peloponissos. Place of helding Ancient Olympics dating from 8th BC century,
- Epidavros in Peloponissos. The most preserved ancient open air classical theatre,
- Delphi in Central Greece. Ancient temples and oracles area dating from 9th BC century,
- Knossos in Crete. Place of origin of ancient islandic Minoan civilisation dating from 18th BC century,
- Meteora in Thessaly. Byzantine era monasteries area set on the top of magnificent huge rocks.
These are the main arcaelogical attractions. Most of the antiquities areas except Knossos in Crete and some destinations in Naxos, Santorini, Mykonos and Rhodes are located in the mainland. So, you can visit them in coach tours departing from Athens.
Take a look at Greece maps provided in this site to have some scratch image of their location and the distances and start some survey in this and linked sites too to clarify these choices.
So i think it would be a really good idea ( and only if you think it fits your rythm ) to make a programme like this: 4 days in Athens, 3 - 5 days in a tour starting from Athens visiting the mainland like Olympia and Delphi and finally 4 - 5 days in Chania or Rethymno on Crete to visit this spectacular island, relax and enjou the food and the people. A well planned trip is always something good. Hope i was helpfull.