Just returned from four days/ three nights in Avignon. We did NOT feel safe at night in this city. Overall very nice place during the day. Historic. Nice shopping. Many narrow , winding streets. Disorienting at times but still easy to walk around due to small size.
But beware of many street people for such a small city and aggressive panhandling even during the daytime. At night, forget it --- the back streets are barren except for a few small squares, and you never know who you'll encounter when you turn down any street. One drunken man was very threatening and aggressive. We found ourselves alone and weren't sure how that episode was going to end. No police to found anywhere, day or night.