If it was me (which it isn't) I would go PE-Acapulco-Mexico City-57 all the way through Queretaro-San Luis-Monterrey-Laredo-San Antonio etc.
Mexico City isn't hard to drive through as long as you avoid peak times. If you're dead set on avoiding Mexico City you could go up to Oaxaca and then Puebla and then take the Arco Norte all the way round to join the 57 but the first part of that journey is really tough.
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