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Serio's Po-Boys & Deli

133 Saint Charles Ave, New Orleans, LA 70130 (Central Business District)
(504) 523-2668
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Ranked #267 of 1,606 restaurants in New Orleans
Certificate of Excellence 2014
Cuisines: Delicatessen
Neighborhood: Central Business District
11 visitor photos
Restaurant details
Neighborhood: Central Business District
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79 reviews from our community

78% Recommend
    33
    29
    12
    2
    3
Rating summary
    Food
    Service
    Value
    Atmosphere
Date | Rating
  • English first
  • Any
English first
Summit, Mississippi
Contributor
11 reviews 11 reviews
9 restaurant reviews
2 helpful votes 2 helpful votes
5 of 5 stars Reviewed July 23, 2014 NEW

We stopped in here on an excellent food tour (Tastebud Tours) and had a HUGE muffaletta that was absolutely delicious. So fresh, so delicious and oh my gosh we got so full. Definitely the best muffaletta in NOLA, also the original place that made it! It is so good it beat Bobby Flay in a throw down!

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Top Contributor
120 reviews 120 reviews
50 restaurant reviews
77 helpful votes 77 helpful votes
4 of 5 stars Reviewed July 14, 2014

We ate here for lunch because it was close to our hotel and we needed a quick bite. We had the small Roast Beef and ¼ Muffeletta. Both sandwiches were “large” and very filling. The Roast Beef was very tender and had some gravy on it, yummy. (Next time we would order it without cheese.) The olive salad on the... More

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Worldwide
Senior Contributor
32 reviews 32 reviews
19 restaurant reviews
9 helpful votes 9 helpful votes
4 of 5 stars Reviewed July 10, 2014

This is a very unassuming shop-front and the trading hours seem kind of restricted for New Orleans however the po-boys are top notch. Just a 2 minute walk from the top of Bourbon St makes it easy to find

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Saint Jerome, Canada
Top Contributor
60 reviews 60 reviews
38 restaurant reviews
21 helpful votes 21 helpful votes
4 of 5 stars Reviewed July 1, 2014

What's a muffuletta? One of the best sandwich you can have in south USA! Different and tasty, you can't go in New-Orleans and not having a bite, it's a must!

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Newtown, Pennsylvania
Contributor
12 reviews 12 reviews
11 restaurant reviews
5 of 5 stars Reviewed June 12, 2014

We go to Nawlins a few times a year and Mike Serio's should never be missed, its a Muffuletta and Po-Boy heaven! I get a different one each time but The Saint is my current fav; wifey loves their tuna and RayRay gets the fried shrimp. We always get a few to go for the way home. Say hi to... More

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Belton, Texas
Contributor
19 reviews 19 reviews
5 restaurant reviews
2 helpful votes 2 helpful votes
5 of 5 stars Reviewed May 28, 2014

They have a wide selection of Po Boy's, and All of them are good. You will never go wrong in NO with a Roast Beef Po Boy Dressed with Debris. Just be sure you get plenty of Napkins.

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Reviewer
3 reviews 3 reviews
3 restaurant reviews
5 of 5 stars Reviewed May 21, 2014 via mobile

Very good ..... Lunch only but the muffalettas are the best by far..."............. Nice people , I would go back again for sure. Maybe try The Mickey ...

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Roanoke, Virginia
Top Contributor
155 reviews 155 reviews
41 restaurant reviews
63 helpful votes 63 helpful votes
4 of 5 stars Reviewed May 19, 2014

We picked up food on two occasions while visiting New Orleans. We had oyster po boys and later Muffalettas. Both were very good and freshly made. I must admit the Muffaletta was even better the next day. We found the large one to be enough for us for 2 meals. The service was prompt. We recommend.

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Greenville, South Carolina
Senior Reviewer
7 reviews 7 reviews
6 restaurant reviews
3 helpful votes 3 helpful votes
5 of 5 stars Reviewed May 18, 2014

We learned of this place via a culinary tour (gotta plug 'em: Tastebud Tours). Serio's is excellent. Must order the Muffaletta!! We actually picked one up on our way to the airport for one final taste of heaven until our next trip back to New Orleans.

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Paris, France
Senior Contributor
25 reviews 25 reviews
18 restaurant reviews
8 helpful votes 8 helpful votes
2 of 5 stars Reviewed May 17, 2014

I just had a po'boy meatball there. I think it was too expensive for the low quality of the food. Nothing special. Subway does it better and les expensive

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