Panacea is a great place to just chill end enjoy a cup of coffee. We usually buy a couple of the dark roast to take home until we can get back to Waynesville.

This coffee house is immensely large and has a boho look to it. There is also a back patio to the shop over looking the river, which is tranquil. The coffee is really great, they add a coffee bean to your coffee & that adds a little touch of chic to it. The food is pretty good, its not to... More

My husband and I visited this restaurant at the advice of a friend. He particularly liked the warehouse atmosphere and the coffee. I ordered the Tarzan and Jane salad and could not eat it. The dish consisted of a large load of coconut, pineapple, granola, and cranberries on mixed greens. It was not good. My husband ordered the grilled Chicken... More

Great sandwiches and wraps and tea and coffee and ambiance - especially like being out on the back deck on the creek in good weather. Then I can walk a block down to the art and pottery shop for a nice visit and a great afternoon getaway.

I don't 'like places where you have to work so hard to get some coffee and a pastry. The atmosphere is cute, a step back to coffee house days but the service is not great.. the coffee is good, the salads and sandwiches are pretentious and average.

Visiting adorable Waynesville over the holidays, we were invited to Panacea for lunch. It resembles a NY city loft, open, wood, with the aroma of coffee. They grind their own and sell it. The lunch menu is varied and innovative. I had the vegetable cheese soup which was perfect for a chilly day. The half sandwich was on a fresh... More

Just spent lunch at Panacea and was very disappointed! My husband ordered the Devilicious Panini and it arrived with about two slices of turkey total (see picture). This sandwich is $9.55. The price is totally unjustified for the amount of meat on the sandwich! They serve their sandwiches with pretzels and fruit. The apple slices still had seeds. They didn't... More

What an awesome place. It was wonderful to see that they have keep the building that way it was instead of trying to modernizing it!!! Great Job!!! You have to try the Hen House or the Devilious (turkey and brie....Yum). Both indoor and outdoor dining....love sitting by the creek it was very peaceful. The smell of coffee when you walk... More

A must stop for visiters. Internet hot spot makes it even better. Wife and I had lun ch here in between cups of hot chocolate and liked it too!