TripAdvisor is the worlds largest travel site, with 737 traveler reviews, 288 candid photos, and prices for 14 hotels in Santee, South Carolina. Powered by advice from real travelers, TripAdvisor offers you reviews of the best hotels in Santee.
We also partner with other top travel sites to make it easy for you to find the best price. For accommodations in Santee, our partners include Priceline, Tingo, Choice Hotels, Hotwire, Agoda, Hilton Hotels, Best Western, Expedia, Venere, Travelocity, Hotels.com and Booking.com. These partners may vary by individual hotel, as featured near the top of each hotel page.