TripAdvisor is the worlds largest travel site, with 766 traveler reviews, 295 candid photos, and prices for 15 hotels in Santee, South Carolina. Powered by advice from real travelers, TripAdvisor offers you reviews of the best hotels in Santee.
We also partner with other top travel sites to make it easy for you to find the best price. For accommodations in Santee, our partners include Expedia, Venere, Travelocity, Booking.com, Hilton Hotels, Choice Hotels, Priceline, Tingo, Agoda, Hotels.com and Best Western. These partners may vary by individual hotel, as featured near the top of each hotel page.